With a 105-yard kickoff return from Percy Harvin to begin the game and a 77-yard punt return from Marcus Sherels, the Minnesota Vikings had enough to defeat the Detroit Lions 20-13 to improve to 3-1.

The Vikings had a -3.2 deficit in The Trench Counter, averaging just 3.8 yards per pass and recorded eight fewer first downs. The Lions had a +6 edge in Total Rushes/Completions.

Christian Ponder went 16-for-26 for 111 yards, but didn't commit a turnover. Adrian Peterson rushed 21 times for 102 yards.

Matthew Stafford went 30-for-51 for 319 yards but couldn't get Calvin Johnson going and the running game was held to a 2.8 yards per carry average.

The Tennessee Titans defeated the Detroit Lions by a final score of 44-41 in a wild overtime game that featured 46 total points in the fourth quarter and a Hail Mary catch by Titus Young.

The Titans had a 3.7 deficit in The Trench Counter, as they had 15 fewer first downs and though they did average 0.9 more yards per play. Detroit had a +48 edge in Total Rushes/Completions, as they ran 91 total plays compared to 61 by the Titans.

Locker went 29-for-42 for 378 yards and two touchdowns without an interception. Nate Washington caught three balls for 112 yards and a touchdown.

Chris Johnson, however, struggled again to get going as he rushed 14 times for 24 yards.

The Titans scored two touchdowns on special teams and a third on defense.

Matthew Stafford went 33-for-42 for 278 yards and a touchdown before leaving with an injury. The Lions settled for four Jason Hanson field goals as their drives stalled.

Shaun Hill threw for 172 yards on 10-for-13 passing and two touchdowns after coming in for Stafford in the fourth quarter.

Calvin Johnson caught 10 balls for 164 yards and a touchdown.

Mikel Leshoure established the running game for the Lions, carrying 26 times for 100 yards and a touchdown.

Matthew Stafford is undergoing an MRI on his strained right leg muscle.

Stafford aggravated the injury in Week 3's loss to the Titans during an interception.

The Lions have a bye in Week 5, which could give Stafford extended rest while only missing one game.

The Detroit Lions will workout both Steve Slaton and Ryan Grant this week as they look to improve the running back position.

Mikel Leshoure was reinstated from his suspension on Monday.

The San Francisco 49ers defeated the Detroit Lions by a final score of 27-19 behind another punishing performance from their defense.

The 49ers had a +9.2 advantage in The Trench Counter, rushing for 5.5 yards per carry against 3.2 for the Lions, along with a +9 edge in first downs. San Francisco held a +2 advantage in Total Rushes/Completions, though several of Matthew Stafford's completions came on the final drive against a prevent defense.

Alex Smith went 20-for-31 for 226 yards, two touchdowns to Vernon Davis and no interceptions. Davis caught five balls for 73 yards.

Frank Gore and Kendall Hunter again gave the 49ers a controlling ground game. Gore had 17 carries for 89 yards and a touchdown.

Stafford went 19-for-32 for 230 yards, a late touchdown to Brandon Pettigrew and an interception. Kevin Smith rushes 16 times for 53 yards.

The 49ers' defense successfully stopped the Lions on several third downs in their own territory, forcing four field goals on five attempts. The Lions were 6-for-15 on third down.

The Detroit Lions will work out Steve Slaton next week in an attempt to add depth to the running back position.

Slaton worked out on Saturday for the Chicago Bears.

The San Francisco 49ers used A.J. Jenkins to play the part of Calvin Johnson in practice on Wednesday.

Jenkins was part of the 49ers' active roster in Week 1 against the Packers, but did not play.

Johnson sat out of Lions' practice on Wednesday with a foot injury.

Jenkins was the 49ers' first round pick in 2012.

The Denver Broncos had the best DVOA in Week 1 as they defeated the Pittsburgh Steelers, followed by the Baltimore Ravens over the Cincinnati Bengals and New England Patriots over the Tennessee Titans.

Football Outsiders also has a stat calle DAVE, which stands for DVOA Adjusted for Variation Early. After Week 1, DAVE accounts for 90 percent and the current VOA counts for 10 percent.

The Patriots rank first in DAVE at 41.0%, followed by the Falcons, Packers, Bears and Ravens. 

Here are the full rankings for DAVE with the preseason DVOA ranking in parentheses: 

1. Patriots (1)
2. Falcons (3)
3. Packers (2)
4. Bears (6)
5. Ravens (7)
6. Jets (8)
7. Broncos (11)
8. Saints (5)
9. Steelers (4)
10. Texans (13)
11. Eagles (12)
12. Cowboys (14)
13. Panthers (10)
14. Giants (9)
15. Buccaneers (22)
16. Lions (21)
17. Chiefs (15)
18. 49ers (23)
19. Chargers (19)
20. Bills (16)
21. Titans (17)
22. Redskins (20)
23. Raiders (24)
24. Bengals (18)
25. Vikings (29)
26. Seahawks (28)
27. Jaguars (26)
28. Dolphins (25)
29. Colts (27)
30. Cardinals (30)
31. Browns (31)
32. Rams (32)

The Detroit Lions had four players in their secondary in Week 1 with no regular season experience playing together.

Safety Louis Delmas and cornerback Chris Houston were sidelined in the game.

The Lions held Sam Bradford to 198 yards passing and one touchdown.

"I think a lot of that went beyond just those four guys," Jim Schwartz said. "It was our linebackers and our d-line. Our d-line did a good job rushing, particularly inside. Corey Williams, Ndamukong Suh, Nick Fairley, Sammie Hill, all those guys made contributions inside.

"I think it was a team effort when it came to that, but guys like Jacob Lacey came in; Bill Bentley played really well until he left the game; (John) Wendling and (Erik) Coleman, two veteran players, did a really nice job."

The secondary has been an issue of concern for the Lions.

Matthew Stafford threw three interceptions, but marched the Detroit Lions down the field to eventually find Kevin Smith on a five-yard touchdown pass with 10 seconds remaining in the game to defeat the St. Louis Rams by a final score of 27-23.

The Lions had a +6.3 advantage in the Trench Counter, recording twice as many first downs and averaging 6.4 yards per play compared to just 4.6 for the Rams. St. Louis had a +3 advantage in turnovers, including one that Cortland Finnegan returned for a touchdown, which gave Jeff Fisher a chance to win his debut.

Stafford threw for 355 yards on 32-48, with six of the completions going to Calvin Johnson for 111 yards.

Sam Bradford completed 17 of his 25 passing attempts for 198 yards and one touchdown.