Houston Texans running back Dameon Pierce is active for Sunday's game against the Jacksonville Jaguars as he returns from an ankle injury.

Pierce, who had been listed as questionable, has appeared in seven games this season for Houston, rushing for 327 yards and a touchdown on 109 carries. He is second on the team in rushing, behind Devin Singletary (471).

Based on how 49ers running back Christian McCaffrey stepped to the podium after Sunday's resounding win over the Jaguars, it would have been difficult to tell that he had just narrowly missed a chance to own the NFL record for consecutive games with a touchdown all to himself.

Instead, McCaffrey actually had some material ready for the inevitable questions that followed his 17-game touchdown streak ending on the same day as his team's three-game losing streak with a 34-3 victory against the Jaguars.

"I suck," McCaffrey said, a smile creeping across his face. "Everyone else on the team scored. Except me."

San Francisco 49ers left tackle Trent Williams, who is dealing with a right ankle sprain, is expected to play on Sunday at the Jacksonville Jaguars, a source told ESPN's Adam Schefter.

Williams is listed as questionable for the game. He returned to practice Thursday and Friday on a limited basis.

Amidst a surge of defensive struggles over their past three games, the San Francisco 49ers have been searching for answers to get back to the dominant unit that spearheaded a 5-0 start.

The Niners made their biggest move last week, trading a compensatory third-round pick to the Washington Commanders for defensive end Chase Young. They're making another, much smaller move this week in the form of an elevator ride.

San Francisco defensive coordinator Steve Wilks, who is in his first year with the team, will move from the coach's booth upstairs to field level to call Sunday's game against the Jacksonville Jaguars, coach Kyle Shanahan announced Wednesday.