The Arizona Cardinals defeated the Detroit Lions 25-21 as both teams are now 1-1.

The Cardinals had a +9.9 advantage in the Trench Counter, finishing with eight more first downs and limiting their penalty yards to 40 compared to 101 for the Lions. Arizona had a +4 edge in Total Rushes/Completions.

Carson Palmer went 22-for-39 for one touchdown and one interception.

Rashard Mendenhall carried 15 times for 66 yards and a touchdown that put the Cardinals out ahead in the final two minutes of the fourth quarter.

Matthew Stafford went 24-for-36 for 278 yards and two touchdowns in the first quarter to Calvin Johnson. Johnson finished with 116 yards receiving.

The St. Louis Rams defeated the Arizona Cardinals 27-24 with a 14-0 fourth quarter.

The Rams had a -2.0 deficit in The Trench Counter, completing five fewer first downs with comparable per play averages. Arizona also had a +1 edge in Total Rushes/Completions.

Jared Cook caught seven balls for 141 yards and two touchdowns to lead the Rams, while Sam Bradford went 27-for-38 for 299 yards and an interception.

Daryl Richardson carried the ball 20 times for just 63 yards.

Larry Fitzgerald caught two touchdown passes from Carson Palmer, who had an interception and a lost fumble.