The Arizona Cardinals suffered their first loss of the season when Kyler Murray threw an interception in the end zone in the final seconds of Thursday night's game against the Green Bay Packers.

A.J. Green never turned around as Murray targeted him in the right corner of the end zone, leading to a game-sealing interception by Rasul Douglas.

Kliff Kingsbury said that "it wasn't the route that we thought we had checked and so we've got to communicate better in those situations." He called the play they expected to run a "safe throw" and Murray said he wasn’t sure what went wrong.

"I honestly don't know what happened," Murray said. "Miscommunication."

J.J. Watt will undergo surgery on his shoulder, which will likely end his 2021 season.

The recovery is likely at least three months.

Watt signed with the Arizona Cardinals this past offseason on a two-year, $28 million deal with $23 million guaranteed. 

The Philadelphia Eagles are trading Zach Ertz to the Arizona Cardinals, according to sources.

Philadelphia will receive cornerback Tay Gowan and a 2022 fifth-round pick in the deal.

Ertz caught a touchdown pass in the Eagles' 28-22 loss to the Tampa Bay Buccaneers on Thursday night.

The Arizona Cardinals have had three positive COVID-19 tests this week, according to a source.

The positive tests include one player and two members of the staff.

Chandler Jones was put on the reserve/COVID-19 list Tuesday because of a positive test.

Since he's vaccinated, in order for Jones to return to the Cardinals, he needs to have two negative tests 24 hours apart and be asymptomatic for 48 hours.

Kyler Murray has overtaken Patrick Mahomes as the consensus favorite to win NFL MVP at U.S. sportsbooks.

Murray, at +550, is the favorite to win the Associated Press MVP award at Caesars Sportsbook. Mahomes is next at +600, followed by Josh Allen at +800.

The Arizona Cardinals quarterback entered the season at 25-1 to win MVP, but he quickly moved into the top tier of favorites and was 10-1 after Week 1.

Murray is completing 76.1% of his passes and has accounted for 12 touchdowns.