Christian McCaffrey is expected to miss multiple weeks though he is unlikely to be placed on injured reserve.

McCaffrey suffered a hamstring injury during the first half of the Carolina Panthers' Week 3 win over the Houston Texans.

Antonio Brown has been placed on the reserve/COVID-19 list.

Brown, like every one of his teammates and all members of the Bucs' coaching staff, is fully vaccinated, and per NFL rules, needs two negative tests 24 hours apart to return, as long as he is asymptomatic.

Brown's 138 receiving yards through two games is second-most on the team this season.

The Cleveland Browns have ruled out Odell Beckham Jr. for their Week 2 game against the Houston Texans.

The Browns also ruled out Beckham shortly before week 1.

Kevin Stefanski said that Beckham would keep practicing on a limited basis and had not suffered any setback as he continues to work his way back from the left knee injury.

Beckham had surgery on the knee after suffering a torn ACL in Week 7 of last season.

Raheem Mostert has announced he will miss the remainder of the 2021 season with knee surgery.

Mostert was injured in Week 1 against the Detroit Lions.

Jerry Jeudy is expected to miss four to six weeks with a high ankle sprain. 

Vic Fangio confirmed Monday that an MRI on Jeudy's ankle revealed the sprain.

"He's definitely got a high ankle sprain, everything else checked out good,'' Fangio said. "He's going to miss some time.''

The Denver Broncos selected Jeudy with the 15th overall pick.

The San Francisco 49ers have lost Raheem Mostert for about eight weeks because of "chipped cartilage" in his knee. The injury requires arthroscopic surgery and lands Mostert on injured reserve.

Elijah Mitchell had 19 carries for 104 yards for the 49ers while JaMycal Hasty had a touchdown.

Trey Sermon was inactive after spending most of the preseason backing up Mostert. 

The Baltimore Ravens believe Gus Edwards suffered a torn ACL during practice on Thursday.

The Ravens previously lost J.K. Dobbins and Justice Hill at running back. 

Marcus Peters is also believed to have suffered a torn ACL at practice.