The Arizona Cardinals defeated the Detroit Lions 25-21 as both teams are now 1-1.

The Cardinals had a +9.9 advantage in the Trench Counter, finishing with eight more first downs and limiting their penalty yards to 40 compared to 101 for the Lions. Arizona had a +4 edge in Total Rushes/Completions.

Carson Palmer went 22-for-39 for one touchdown and one interception.

Rashard Mendenhall carried 15 times for 66 yards and a touchdown that put the Cardinals out ahead in the final two minutes of the fourth quarter.

Matthew Stafford went 24-for-36 for 278 yards and two touchdowns in the first quarter to Calvin Johnson. Johnson finished with 116 yards receiving.