The San Francisco 49ers have gone three-and-out on 43.1 percent of their offensive series through the first four weeks of the season. The 49ers have the fourth highest percentage in the NFL in that category.

The 49ers scored just a combined 10 points in losses against the Seattle Seahawks and Indianpolis Colts.

But the defense has forced three-and-outs 39.6 percent of the time, which ranks fifth.