The San Francisco 49ers' offensive line struggled to begin the 2011 season, but have been excellent to begin the 2012 campaign.

The 49ers rank second in rushing yards per attempt at 5.4.

“Big, strong and physical,” Bills coach Chan Gailey said of the line. “I mean, they’re playing extremely well. They are a strong bunch. They’re probably overall the best group we’ve played this year.”

“I think last year we were only in week four of learning the offense,” Joe Staley said. “We had a new coaching staff. That really affects the offensive line. We all know the plays, but we were still trying to figure each other out and try to figure out the offense. Now we’re so much further along.”