San Francisco 49ers leading receiver Brandon Lloyd left Sunday's game against Jacksonville with a sprained neck.
Lloyd was injured in the first half, and team officials later announced he wouldn't return.
Lloyd caught one pass for 6 yards in the game, giving him 42 receptions for 667 yards this season. He also has a team-high four touchdowns.
The 49ers already were without their other starting receiver, Arnaz Battle, who missed the game with a knee injury.
Lloyd Leaves With Sprained Neck