It remains to be seen if Peyton Manning will ever play another down in the NFL, but the first retirement report has already hit the internet. Actor Rob Lowe, a Colts fan, wrote on his Twitter account Wednesday afternoon that Manning will retire. Lowe says that his "people" say it will happen Wednesday. "Hearing my fave, #18 Peyton Manning will not return to #NFL. Wow. #Colts," Lowe wrote. Since the "news" broke, Tom Condon, the agent for Manning, has come out with a denial.