San Francisco wide receiver Isaac Bruce needs just 60 yards in the season's final two games to surpass Tim Brown on the all-time list.
Brown has 14,935 yards, with Jerry Rice in first place with 22,895 yards.
"It means a lot," Bruce said. "We've shared some things -- ups, downs, in-betweens. It's special. Still live there, so it's special."
The 49ers will battle Bruce's old team, the Rams, on Sunday.
49ers' Bruce Needs 60 Yards To Pass Brown