Bills rookie running back C.J. Spiller was the team's main option in their preseason victory over the Colts on Thursday night. Spiller rushed 10 times for 54 yards, scoring on a brilliant 31-yard rush to open the game. He was targeted once through the air and grabbed a two-yard reception. He was featured after veterans Fred Jackson and Marshawn Lynch were injured earlier in the week. "I think you can see tonight why we drafted C.J.," coach Chan Gailey said of the player selected ninth overall out of Clemson. "Obviously, running the ball is what he does best. And he made an unbelievable run on that touchdown."