The Colts are denying a report that quarterback Peyton Manning had a staph infection that forced doctors to operate on his knee a second time this offseason. The Indianapolis Star reported the second surgery on Friday. "Peyton Manning developed swelling in his left pre-patella bursa in late February," the Colts said in a statement. "The swollen bursa was treated conservatively beginning in February with drainage and anti-inflammatory medication. "The first signs of infection occurred while he was in New Orleans in July. It should be noted that infection developed prior to any surgery. Upon manifestation of the signs of infection, he immediately had surgery to remove the bursa sac. Concurrently, he was treated aggressively with antibiotics, and the infection was eliminated. "The second procedure [tacking of the skin to eliminate the bursal space] was designed to ensure the complete and swift resolution of the bursal problem. The procedure was successful. "The second procedure was in no way, shape or form, related to the infection. The second procedure did not delay his rehabilitation or recovery materially."