Frank Gore, the 49ers Pro Bowl running back, broke a bone in his right hand Monday during the first padded practice of training camp and might not play in the preseason. Gore was injured during a non-contact ball-handling drill, and coach Mike Nolan said he would not practice with the team for the remainder of the week. Gore will be re-evaluated next Monday, and Nolan expects him to return to practice then with a cast on his hand. "He'll be ready for the latter part of preseason, but his participating in the preseason, we'll wait and see on that," Nolan said.