The San Francisco 49ers saw three running backs go down with injuries in their 17-11 win over the Philadelphia Eagles on Sunday afternoon.

The injuries came after they lost starter Raheem Mostert to a season-ending knee injury in Week 1.

First, it was starter Elijah Mitchell's right shoulder, then it was an ankle injury for JaMycal Hasty, and finally it was a concussion for Trey Sermon.

The Niners finished with 117 yards on 38 carries, an average of just 3.1 yards per attempt.