The San Francisco 49ers will start Nick Mullens at quarterback for Game 3 at the New York Giants with Jimmy Garoppolo injured.

Mullens will be making his first start since Dec. 30, 2018, which was the final appearance in an eight-game stretch for him as the starter after Garoppolo tore his left ACL in Week 3 of that season. He threw for 2,277 yards with 13 touchdowns and 10 interceptions for a passer rating of 90.8 as the Niners went 3-5 in his starts.

C.J. Beathard will serve as backup.

The 49ers will also be without George Kittle and Raheem Mostert.