The San Francisco 49ers are likely to start Nick Mullens at quarterback in Week 3 against the New York Giants.
Jimmy Garoppolo's sprained ankle is expected to sideline him.
"I'll be surprised if Jimmy gets back later in the week," Kyle Shanahan said. "Nick is ready to go. He got a lot of playing time with us in 2018, and that prepared him for moments like this."
Mullens started eight games for the 49ers in 2018.