Leonard Fournette will be out indefinitely after aggravating his right hamstring.
Doug Marrone also said he's unsure when the team will be able to determine how much time Fournette will miss.
"I really don't know," Marrone said. "Believe me, if I knew exactly what the deal was and I could tell you -- three [games], six, 10, IR, whatever -- I would. I just don't know. Those injuries are tough. We talked about it by position. We talked about it by player. We've talked about it every other way. "I thought he was looking good. ... You guys see him working [in practice] ,but it's different when you're playing a game. The game's different."