Papa John's and the NFL have mutually decided to end their sponsorship agreement.
The brand became the official pizza of the NFL in 2010.
The company said on an earnings call that there was no additional cost for undoing the deal.
"The NFL and Papa John's have made a mutual decision to shift from their official league sponsorship to a focus on partnerships with 22 local NFL teams, presence in broadcast and digital media, and key personalities in the sport," the league and company said in a joint statement.
John Schnatter suggested that protests during the national anthem hurt Papa John's business.
"We are disappointed the NFL and its leadership did not resolve this," Schnatter said at the time.
Schnatter later apologized after the company's stock dropped 12 percent. Schnatter was also replaced as CEO.