Vincent Jackson's return to the Chargers lasted just two plays on Sunday night against the Colts.
Jackson sat out the first seven games of the season due to a contract dispute and the last three while serving a suspension.
He started the game against Indianapolis and was on the sideline for good by the time the Chargers took their third snap.
The Chargers explained the departure as a "calf injury."
Vincent Jackson's Return Lasts Two Plays