Ryan Clady tore his left ACL during practice on Wednesday and will likely miss the entire 2015 season.

Clady was injured while blocking on a pass play during an 11-on-11 drill. He was treated by trainers after he went down and did not participate for the rest of the practice, but he remained on the field, limping slightly.

"He pulled himself out (of drills), said his knee was sore," Broncos coach Gary Kubiak said. "We really weren't that worried last night, everybody felt good, but we felt like we'd take a look at it this morning, and unfortunately we got some horrible news."

Clady previously blew out his left knee in a pickup basketball game in April 2010, but returned to start every game for Denver that season.

This will be his fourth major surgery in the last five years, with the others coming on his left knee, shoulder and foot.

A first-round pick in 2008, Clady is the last remaining player from Mike Shanahan's 14-year tenure as Broncos coach.

A four-time Pro Bowler and two-time first-team All-Pro, Clady has started 16 games in six of his seven NFL seasons. 

Peyton Manning is still getting accustomed to the Denver Broncos' new offense under Gary Kubiak.

Manning has been more comfortable operating from the shotgun late in his career, but he's coming up to the line of scrimmage on almost all of his snaps right now.

"We know the other end of the stick is fine. It's something he's been doing forever," Kubiak said. "So, we're going to spend a lot of time under center initially. ... He's been very responsive and he's working extremely hard."

After what he called the Broncos' "first real day of practice in shoulder pads," Manning said he's eager to smooth out the roughness in this new hybrid offense, saying, "I feel I can do whatever they ask me to do."

Some believe quarterbacks like the shotgun because they don't have to take their eyes off the pass rush.

Peyton Manning has been affable pitchman in commercials, but his qualities as a teammate have been uneven.

Manning once called Mike Vanderjagt an "idiot kicker" and there's been countless shots over the years visibly disgusted with the performance of teammates.

Orlando Franklin signed with the San Diego Chargers this offseason and he's enjoyed working with Philip Rivers.

"One thing I noticed immediately when I got here is that Philip Rivers is definitely more approachable than Peyton," Franklin said on Pro Football Talk on NBC Sports Network. "I don't know if it was because I was a lot younger being that I met Peyton in my second season and now meeting Philip going into my fifth season but definitely I will say Philip is more approachable than Peyton."

Jeff Heuerman suffered a torn ACL in Saturday and is expected to miss the 2015 season.

The Denver Broncos drafted Heuerman with the 92nd overall pick.

Heuerman was expected to help the Broncos replace Julius Thomas at tight end.

"I feel terrible for Jeff and this is an unfortunate situation," Gary Kubiak said. "Jeff was going to be a big part of our team this year, and he's still going to be a big part of our team and organization in the future.

"He'll get well and be with us as part of this team throughout his rehabilitation."

The Denver Broncos traded up to No. 23 to select Shane Ray.

Ray was No. 10 on the Broncos' board.

Ray will join Von Miller and DeMarcus Ware to form one of the NFL's best pass rushes.