Christian McCaffrey won't play in the Carolina Panthers' Week 8 game on Thursday night against the Atlanta Falcons with his high ankle sprain.
McCaffrey returned to practice Monday and on Tuesday was given a designation to return from injured reserve.
McCaffrey suffered the injury during a Week 2 loss to Tampa Bay.
Carolina is 3-2 without McCaffrey as Mike Davis has averaged more than 100 yards from scrimmage in his first four games.