49ers wide receiver Michael Crabtree could miss four to six weeks because of a lingering foot issue, according to a report. San Francisco issued a press release announcing that Crabtree was placed on the physically unable to perform list, but they didn't say how long he'd be out. If Crabtree can't pass a physical before the beginning of the regular season in September, he must remain on the PUP list for six weeks.

The Colts won't have Peyton Manning when training camp starts as he continues to recover from offseason neck surgery. The quarterback won't be ready to participate with the rest of his teammates July 31, when the team is scheduled to begin camp assuming a labor settlement is reached, according to a report by The Indianapolis Star. Manning is rehabbing from his second neck-related surgery in 15 months. The two procedures were not related.

Colts quarterback Peyton Manning has conceded that the neck surgery he had May 23 to correct a bulging disk and the lockout have put him in a "cautious" mode on being physically active. "The lockout didn't allow me to work my (Colts) therapist, Erin Barill, and I'm just not comfortable taking any chances with this thing," Manning said. "Erin knows me. He's rehabbed me through two other surgeries (neck and knee) and I think most people understand that once you build up a trust with your therapist, that's the guy you want and need to work with." He said he had "no idea" when he will be able to participate in training camp until he gets an assessment from Barill. He has been rehabbing with other therapists. Manning, 35, is rehabbing from his second neck-related surgery in 15 months.

Jaguars running back Maurice Jones-Drew says his surgically-repaired knee should be 100 percent within three to four weeks. Jones-Drew listed himself as currently 80-85 percent after January's surgery to repair a torn meniscus in his left knee. The five-year veteran was hampered by knee pain for most of last season, but still managed to rush for 1,324 yards and five touchdowns.