Seantrel Henderson of the Buffalo Bills is facing a 10-game suspension for a second violation of the NFL's substance abuse policy.

Henderson, 24, missed the first four games of the season for his initial violation of the substance abuse policy. 

Henderson missed the final five games of last season after he was diagnosed with Crohn's disease. Henderson's agent said the positive test was due to medical marijuana being used to treat the issue.

Henderson discussed medical marijuana use in treating Crohn's disease during an interview with the Buffalo News in October.

"I've got doctors telling me this is the No. 1 medicine that would help your disease," Henderson told the newspaper. "You try to tell that to the league, and it seems like they didn't care too much."