The Carolina Panthers have ruled out Cam Newton for Week 5 with a concussion.

Derek Anderson will start for the Panthers in place of Newton.

"We're going to do what we do, play who we play," said Ron Rivera on Saturday.

"We've done this before. It's that next man up mentality. We've done it before.''

Rivera had no update on Newton's status in the concussion protocol other than "he's progressing."