Ryan Fitzpatrick suffered a fracture in his leg in Sunday's loss to the Colts and will need season-ending surgery, a source confirmed to ESPN.com.

"I felt for him," Texans coach Bill O'Brien said. "I felt for him because he knew right away that it was injured, his leg was injured, and I felt bad for him. He put a lot in for this week."

Fitzpatrick suffered the injury after a 2-yard rush on a 2nd-and-6 play early in the second quarter. He was carted off the field with an air cast on his leg.

"I just saw him take off as he's done so many times," Texans left tackle Duane Brown said. "(It) looked like a regular tackle. He tried to get up and sat back down -- that's when I kind of knew there was something up."