Tyrann Mathieu will have surgery for his fractured and dislocated left thumb and will miss at least three weeks, sources told ESPN NFL Insider Ed Werder on Tuesday.

The Cardinals do not plan on putting Mathieu on injured reserve as they are hopeful he'll return this season, sources told Werder. 

Bruce Arians said Monday that the team's best-case scenario was for Mathieu to have been able to play Dec. 7, against Kansas City.