With losses by Oregon and Kansas State, Notre Dame has ascended to the top slot in the latest AP NCAA football rankings.
Notre Dame received all 60 first place votes.
Ohio State is the only other undefeated team and is ranked fourth behind one-loss SEC schools Alabama and Georgia.
Oregon dropped to fifth and is trailed by Florida, Kansas State, LSU, Texas A&M and Florida State.
Notre Dame will have to beat USC in order to qualify for the BCS National Championship Game.