Dez Bryant has been placed on injured reserve and will undergo surgery on his foot and ankle.

Bryant was limited to just nine games this season after breaking his right foot in the season opener.

At the time of the surgery Bryant had a bone graft to help the healing process, which is standard in how the team deals with foot surgeries.

Bryant signed a five-year, $70 million contract with $45 million guaranteed on July 15 but suffered a hamstring strain early in training camp. 

Dez Bryant has been ruled out for Sunday's game against the Buffalo Bills.

Bryant did not practice during the week because of foot and ankle injuries, and it's likely he won't play again this season.

Bryant said earlier this month he felt as good as he has all season since missing five games following foot surgery after the season opener.

Gary Kubiak said Manning would have a "big workout" on Saturday to evaluate his progress in his rehab from a partially torn plantar fascia in his left foot.

Manning has already been ruled out for Week 16. 

Manning returned to practice on a limited basis last week, but suffered a setback and had to sit out last Friday.

The Dallas Cowboys have finally placed Tony Romo on injured reserve.

The Cowboys went 3-1 in Romo's four starts, but he was not able to finish two games because of a broken left collarbone.

The Cowboys have won just one game without Romo and will miss the playoffs for the fifth time in the past six years.

Drew Brees has a torn plantar fascia in his right foot but he intends to finish out the remaining two weeks of the season.

According to the source, an MRI was sent to Dr. Robert Anderson, the Charlotte specialist who treated Peyton Manning for a similar injury.

Anderson has not yet made a recommendation to Brees, who is believed to be considering several different treatment protocols, the source said.

Brees was hurt during the second quarter of the Saints' loss on Monday.

Andrew Luck has been ruled out for Week 16 by the Indianapolis Colts.

Luck is still recovering from a lacerated kidney.

Matt Hasselbeck is “beat up from the feet up,” according to Chuck Pagano.

LeSean McCoy tore his MCL and will be "week-to-week" pending further evaluation.

Rex Ryan said Monday that McCoy will have an MRI to determine the full extent of the injury, but calling McCoy week-to-week at this point in the year could make it likely that we’ve seen the last of the back this year.

If his year is over, McCoy will finish his first season with the Bills with 203 carries for 895 yards and three touchdowns in 12 games.

Tyrann Mathieu tore his ACL on a late interception in the Arizona Cardinals' win at the Philadelphia Eagles.

Mathieu has been one of the NFL's best defensive backs this season.

Bruce Arians says he loves the fact that Mathieu has used his second chance perfectly, becoming a leader and a great player. 

“It’s his energy and passion, at everything,” said Arians. “He’s just so good to be around, for us coaches and for his teammates. He wants to be great every day. I mean, we could lose Carson [Palmer], or Patrick [Peterson], and it’d be devastating. We could replace Tyrann, but who would replace his interceptions and his sacks? I have to say, he’s my favorite. This would be devastating for him.”

T.J. Yates suffered a torn ACL in the Houston Texans' win at the Indianapolis Colts.

Yates was the Texans' backup quarterback with Brian Hoyer out due to a concussion.

Brandon Weeden finish the game for the Texans.

Marcus Mariota could miss the final two games of the season with a knee injury.

Mariota missed time earlier this season with a knee issue and injured it in Week 15.

If Sunday was his finale, Mariota will finish his rookie season with 2,818 passing yards, 19 touchdowns and 10 interceptions.